Reaction Details Report a problem with these data
Target
P2X purinoceptor 4
Ligand
BDBM50399190
Substrate
n/a
Meas. Tech.
ChEMBL_876876 (CHEMBL2184470)
IC50
4040±n/a nM
Citation
 Hernandez-Olmos, V; Abdelrahman, A; El-Tayeb, A; Freudendahl, D; Weinhausen, S; Müller, CE N-substituted phenoxazine and acridone derivatives: structure-activity relationships of potent P2X4 receptor antagonists. J Med Chem 55:9576-88 (2012) [PubMed]  Article 
Target
Name:
P2X purinoceptor 4
Synonyms:
P2RX4_RAT | P2rx4 | Purinergic, P2X4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43504.16
Organism:
RAT
Description:
Purinergic, P2X4 0 RAT::P51577
Residue:
388
Sequence:
MAGCCSVLGSFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKAKGVAVTNTSQLGFRIWDVADYVIPAQEENSLFIMTNMIVTVNQTQSTCPEIPDKTSICNSDADCTPGSVDTHSSGVATGRCVPFNESVKTCEVAAWCPVENDVGVPTPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTSYLKSCIYNAQTDPFCPIFRLGTIVEDAGHSFQEMAVEGGIMGIQIKWDCNLDRAASLCLPRYSFRRLDTRDLEHNVSPGYNFRFAKYYRDLAGKEQRTLTKAYGIRFDIIVFGKAGKFDIIPTMINVGSGLALLGVATVLCDVIVLYCMKKKYYYRDKKYKYVEDYEQGLSGEMNQ
  
Inhibitor
Name:
BDBM50399190
Synonyms:
CHEMBL2180149
Type:
Small organic molecule
Emp. Form.:
C26H21NO
Mol. Mass.:
363.451
SMILES:
OC1(c2ccccc2)c2ccccc2N(Cc2ccccc2)c2ccccc12
Structure:
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