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Target
D(2) dopamine receptor
Ligand
BDBM50401947
Substrate
n/a
Meas. Tech.
ChEMBL_886472 (CHEMBL2214283)
Ki
51±n/a nM
Citation
 Löber, S; Hübner, H; Buschauer, A; Sanna, F; Argiolas, A; Melis, MR; Gmeiner, P Novel azulene derivatives for the treatment of erectile dysfunction. Bioorg Med Chem Lett 22:7151-4 (2012) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50401947
Synonyms:
CHEMBL2207638
Type:
Small organic molecule
Emp. Form.:
C28H35N3O
Mol. Mass.:
429.597
SMILES:
COc1ccccc1N1CCN(Cc2cc(CN3CCCCC3)c3cccccc23)CC1
Structure:
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