Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50403353
Substrate
n/a
Meas. Tech.
ChEBML_157883
Ki
150±n/a nM
Citation
Thompson, SK; Eppley, AM; Frazee, JS; Darcy, MG; Lum, RT; Tomaszek, TA; Ivanoff, LA; Morris, JF; Sternberg, EJ; Lambert, DM; Fernandez, AV; Petteway, SR; Meek, TD; Metcalf, BW; Gleason, JG Synthesis and antiviral activity of a novel class of HIV-1 protease inhibitors containing a heterocyclic P1-P2 amide bond isostere Bioorg Med Chem Lett 4:2441-2446 (1994) Article
More Info.:
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF