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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50403897
Substrate
n/a
Meas. Tech.
ChEBML_1825
IC50
2692±n/a nM
Citation
 Baglin, I; Daveu, C; Lancelot, JC; Bureau, R; Dauphin, F; Pfeiffer, B; Renard, P; Delagrange, P; Rault, S First tricyclic oximino derivatives as 5-HT3 ligands. Bioorg Med Chem Lett 11:453-7 (2001) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5HT1B_HUMAN | HTR1B | HTR1DB | S12 | Serotonin (5-HT) receptor | Serotonin 1D beta receptor | Serotonin Receptor 1B
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
43579.17
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells
Residue:
390
Sequence:
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
  
Inhibitor
Name:
BDBM50403897
Synonyms:
CHEMBL334923
Type:
Small organic molecule
Emp. Form.:
C14H17N3OS
Mol. Mass.:
275.369
SMILES:
CN(C)CCO\N=C1\c2cccn2-c2c(C)csc12
Structure:
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