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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50090528
Substrate
n/a
Meas. Tech.
ChEMBL_2532 (CHEMBL616882)
Ki
<10000±n/a nM
Citation
 Riemer, C; Borroni, E; Levet-Trafit, B; Martin, JR; Poli, S; Porter, RH; Bös, M Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist. J Med Chem 46:1273-6 (2003) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT-2A) | 5-hydroxytryptamine receptor 2A (5HT-2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_HUMAN | HTR2 | HTR2A | Serotonin receptor 2A
Type:
undefined
Mol. Mass.:
52607.65
Organism:
Homo sapiens (Human)
Description:
P28223
Residue:
471
Sequence:
MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
  
Inhibitor
Name:
BDBM50090528
Synonyms:
4-Amino-N-(2,6-bis-dimethylamino-pyrimidin-4-yl)-benzenesulfonamide | 4-Amino-N-(2,6-bis-methylamino-pyrimidin-4-yl)-benzenesulfonamide | 4-Amino-N-(2-methylamino-pyrimidin-4-yl)-benzenesulfonamide | 4-amino-N-(2,6-bis(methylamino)pyrimidin-4-yl)benzenesulfonamide | CHEMBL433461 | N-(2,6-bis(methylamino)pyrimidin-4-yl)-4-aminobenzenesulfonamide | Ro 04-6790 | Ro-04-6790
Type:
Small organic molecule
Emp. Form.:
C12H16N6O2S
Mol. Mass.:
308.359
SMILES:
CNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC)n1
Structure:
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