Reaction Details Report a problem with these data
Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50410044
Substrate
n/a
Meas. Tech.
ChEMBL_308167 (CHEMBL834181)
Ki
549.54±n/a nM
Citation
 Garg, R; Patel, D Hydrophobicity in the design of P2/P2' tetrahydropyrimidinone HIV protease inhibitors. Bioorg Med Chem Lett 15:3767-70 (2005) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50410044
Synonyms:
CHEMBL361999
Type:
Small organic molecule
Emp. Form.:
C34H35N5O4
Mol. Mass.:
577.6728
SMILES:
NC(C=O)c1cccc(c1)N1[C@@H](Cc2ccccc2)[C@@H](O)[C@H](CCc2ccccc2)N(C1=O)c1cccc(c1)C(=N)NO
Structure:
Search PDB for entries with ligand similarity: