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Target
Adenosine receptor A1
Ligand
BDBM50242664
Substrate
n/a
Meas. Tech.
ChEMBL_530419 (CHEMBL972184)
Ki
3235936.57±n/a nM
Citation
 Massarelli, I; Coi, A; Pietra, D; Nofal, FA; Biagi, G; Giorgi, I; Leonardi, M; Fiamingo, F; Bianucci, AM QSAR study on a novel series of 8-azaadenine analogues proposed as A1 adenosine receptor antagonists. Eur J Med Chem 43:114-21 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50242664
Synonyms:
CHEMBL455383 | N-(3-benzyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)-4-methoxybenzamide
Type:
Small organic molecule
Emp. Form.:
C25H20N6O2
Mol. Mass.:
436.4653
SMILES:
COc1ccc(cc1)C(=O)Nc1nc(nc2n(Cc3ccccc3)nnc12)-c1ccccc1
Structure:
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