Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 2
Ligand
BDBM50416296
Substrate
n/a
Meas. Tech.
ChEMBL_640109 (CHEMBL1174379)
Ki
>3162.28±n/a nM
Citation
 Peace, S; Philp, J; Brooks, C; Piercy, V; Moores, K; Smethurst, C; Watson, S; Gaines, S; Zippoli, M; Mookherjee, C; Ife, R Identification of a sulfonamide series of CCR2 antagonists. Bioorg Med Chem Lett 20:3961-4 (2010) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 2
Synonyms:
CCR2_MOUSE | Ccr2 | Cmkbr2
Type:
PROTEIN
Mol. Mass.:
42795.68
Organism:
Mus musculus
Description:
ChEMBL_1502265
Residue:
373
Sequence:
MEDNNMLPQFIHGILSTSHSLFTRSIQELDEGATTPYDYDDGEPCHKTSVKQIGAWILPPLYSLVFIFGFVGNMLVIIILIGCKKLKSMTDIYLLNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKVFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVITSVVTWVVAVFASLPGIIFTKSKQDDHHYTCGPYFTQLWKNFQTIMRNILSLILPLLVMVICYSGILHTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLFLTTFQESLGMSNCVIDKHLDQAMQVTETLGMTHCCINPVIYAFVGEKFRRYLSIFFRKHIAKRLCKQCPVFYRETADRVSSTFTPSTGEQEVSVGL
  
Inhibitor
Name:
BDBM50416296
Synonyms:
CHEMBL1171208
Type:
Small organic molecule
Emp. Form.:
C19H13ClFNO5S
Mol. Mass.:
421.827
SMILES:
OC(=O)c1ccccc1Oc1cccc(F)c1NS(=O)(=O)c1ccc(Cl)cc1
Structure:
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