Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50420162
Substrate
n/a
Meas. Tech.
ChEMBL_830235 (CHEMBL2060786)
EC50
630.96±n/a nM
Citation
 Shimpukade, B; Hudson, BD; Hovgaard, CK; Milligan, G; Ulven, T Discovery of a potent and selective GPR120 agonist. J Med Chem 55:4511-5 (2012) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50420162
Synonyms:
CHEMBL2058527
Type:
Small organic molecule
Emp. Form.:
C23H19F3O4
Mol. Mass.:
416.3898
SMILES:
OC(=O)CCc1ccc(OCc2ccccc2-c2ccc(OC(F)(F)F)cc2)cc1
Structure:
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