Reaction Details Report a problem with these data
Target
Somatostatin receptor type 2
Ligand
BDBM50423472
Substrate
n/a
Meas. Tech.
ChEMBL_461986 (CHEMBL944829)
Kd
12023±n/a nM
Citation
 Troxler, T; Enz, A; Hoyer, D; Langenegger, D; Neumann, P; Pfäffli, P; Schoeffter, P; Hurth, K Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor. Bioorg Med Chem Lett 18:979-82 (2008) [PubMed]  Article 
Target
Name:
Somatostatin receptor type 2
Synonyms:
SOMATOSTATIN SST2 | SRIF-1 | SS2R | SSR2_RAT | Somatostatin receptor | Somatostatin receptor 2 | Somatostatin receptor type 2 | Sstr2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41212.21
Organism:
RAT
Description:
SOMATOSTATIN SST2 SSTR2 RAT::P30680
Residue:
369
Sequence:
MELTSEQFNGSQVWIPSPFDLNGSLGPSNGSNQTEPYYDMTSNAVLTFIYFVVCVVGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMINVAVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYAFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSVAISPTPALKGMFDFVVILTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGAEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI
  
Inhibitor
Name:
BDBM50423472
Synonyms:
CHEMBL401309
Type:
Small organic molecule
Emp. Form.:
C27H32ClN5O2
Mol. Mass.:
494.028
SMILES:
CCn1c(cccc1=O)N1CCN(CC1)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c(Cl)[nH]c4cccc2c34)N(C)C1
Structure:
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