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Target
Carbonic anhydrase 2
Ligand
BDBM50426823
Substrate
n/a
Meas. Tech.
ChEMBL_938168 (CHEMBL2328250)
Ki
6800±n/a nM
Citation
 Buchieri, MV; Riafrecha, LE; Rodríguez, OM; Vullo, D; Morbidoni, HR; Supuran, CT; Colinas, PA Inhibition of theß-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: identification of the first inhibitor with anti-mycobacterial activity. Bioorg Med Chem Lett 23:740-3 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CA-II | CA2 | CAC | CAH2_HUMAN | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Homo sapiens (Human)
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50426823
Synonyms:
CHEMBL2323140
Type:
Small organic molecule
Emp. Form.:
C16H20O7
Mol. Mass.:
324.3258
SMILES:
OC[C@H]1O[C@@H](CC(=O)C=Cc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@H]1O |r,w:8.7|
Structure:
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