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Target
D-amino-acid oxidase
Ligand
BDBM50427215
Substrate
n/a
Meas. Tech.
ChEMBL_938788 (CHEMBL2327932)
IC50
>500000±n/a nM
Citation
 Katane, M; Osaka, N; Matsuda, S; Maeda, K; Kawata, T; Saitoh, Y; Sekine, M; Furuchi, T; Doi, I; Hirono, S; Homma, H Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro. J Med Chem 56:1894-907 (2013) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | DAMOX | DAO | OXDA_HUMAN
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Homo sapiens (Human)
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
  
Inhibitor
Name:
BDBM50427215
Synonyms:
CHEMBL2324853
Type:
Small organic molecule
Emp. Form.:
C9H7NO2
Mol. Mass.:
161.1574
SMILES:
O=c1cc([nH]o1)-c1ccccc1
Structure:
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