Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50295926
Substrate
n/a
Meas. Tech.
ChEMBL_943917 (CHEMBL2339884)
Ki
44±n/a nM
Citation
 Rempel, V; Fuchs, A; Hinz, S; Karcz, T; Lehr, M; Koetter, U; Müller, CE Magnolia Extract, Magnolol, and Metabolites: Activation of Cannabinoid CB2 Receptors and Blockade of the Related GPR55. ACS Med Chem Lett 4:41-5 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50295926
Synonyms:
4'-O-methylhonokiol, MH | 4-methoxyhonokiol | 5,3'-Diallyl-4'-methoxy-biphenyl-2-ol | CHEMBL89700 | Magreth-14a | Methylhonokiol
Type:
Small organic molecule
Emp. Form.:
C19H20O2
Mol. Mass.:
280.3609
SMILES:
COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O
Structure:
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