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Target
D(3) dopamine receptor
Ligand
BDBM50430538
Substrate
n/a
Meas. Tech.
ChEMBL_946369 (CHEMBL2346423)
Ki
20±n/a nM
Citation
 Sanna, F; Ortner, B; Hübner, H; Löber, S; Tschammer, N; Gmeiner, P Discovery of dopamine D4 receptor antagonists with planar chirality. Bioorg Med Chem 21:1680-4 (2013) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50430538
Synonyms:
CHEMBL2336892
Type:
Small organic molecule
Emp. Form.:
C30H32N4
Mol. Mass.:
448.6019
SMILES:
C(N1CCN(CC1)c1ccccc1)c1cnn(c1)-c1cc2CCc3ccc(CCc1cc2)cc3
Structure:
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