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Target
CD81 antigen
Ligand
BDBM50434805
Substrate
n/a
Meas. Tech.
ChEMBL_962514 (CHEMBL2390556)
Kd
21±n/a nM
Citation
 Yu, F; Wang, Q; Zhang, Z; Peng, Y; Qiu, Y; Shi, Y; Zheng, Y; Xiao, S; Wang, H; Huang, X; Zhu, L; Chen, K; Zhao, C; Zhang, C; Yu, M; Sun, D; Zhang, L; Zhou, D Development of oleanane-type triterpenes as a new class of HCV entry inhibitors. J Med Chem 56:4300-19 (2013) [PubMed]  Article 
Target
Name:
CD81 antigen
Synonyms:
26 kDa cell surface protein TAPA-1 | CD81 | CD81_HUMAN | CD_antigen=CD81 | TAPA1 | TSPAN28 | Target of the antiproliferative antibody 1 | Tetraspanin-28 | Tspan-28
Type:
PROTEIN
Mol. Mass.:
25805.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_103124
Residue:
236
Sequence:
MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYVGIYILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFSGKLYLIGIAAIVVAVIMIFEMILSMVLCCGIRNSSVY
  
Inhibitor
Name:
BDBM50434805
Synonyms:
ECHINOCYSTIC ACID
Type:
Small organic molecule
Emp. Form.:
C30H48O4
Mol. Mass.:
472.6997
SMILES:
CC1(C)CC[C@@]2([C@H](O)C[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@H]2C1)C(O)=O |r,c:11|
Structure:
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