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Target
Cytochrome P450 1A2
Ligand
BDBM50443623
Substrate
n/a
Meas. Tech.
ChEMBL_1279431 (CHEMBL3096587)
IC50
>20000±n/a nM
Citation
 Suzuki, H; Utsunomiya, I; Shudo, K; Fujimura, T; Tsuji, M; Kato, I; Aoki, T; Ino, A; Iwaki, T Potent oxazolidinone antibacterials with heteroaromatic C-ring substructure. ACS Med Chem Lett 4:1074-8 (2013) [PubMed]  Article 
Target
Name:
Cytochrome P450 1A2
Synonyms:
CP1A2_HUMAN | CYP1A2 | CYPIA2 | Cholesterol 25-hydroxylase | Cytochrome P(3)450 | Cytochrome P450 1A | Cytochrome P450 1A2 (CYP1A2) | Cytochrome P450 4 | Cytochrome P450-P3
Type:
Enzyme
Mol. Mass.:
58423.38
Organism:
Homo sapiens (Human)
Description:
P05177
Residue:
516
Sequence:
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
  
Inhibitor
Name:
BDBM50443623
Synonyms:
CHEMBL3092417
Type:
Small organic molecule
Emp. Form.:
C19H17FN4O3
Mol. Mass.:
368.3617
SMILES:
CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccn2ccnc2c1 |r|
Structure:
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