Reaction Details Report a problem with these data
Target
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Ligand
BDBM50444914
Substrate
n/a
Meas. Tech.
ChEMBL_1281313 (CHEMBL3101286)
Ki
44000±n/a nM
Citation
 Belal, A; El-Gendy, Bel-D Pyrrolizines: Promising scaffolds for anticancer drugs. Bioorg Med Chem 22:46-53 (2013) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Synonyms:
PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
Type:
PROTEIN
Mol. Mass.:
18248.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502595
Residue:
163
Sequence:
MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
  
Inhibitor
Name:
BDBM50444914
Synonyms:
CHEMBL3099730
Type:
Small organic molecule
Emp. Form.:
C22H27N2O5P
Mol. Mass.:
430.4339
SMILES:
OP(O)(=O)OCC1C2CCCN2C(C1C(=O)NCc1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: