Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM50445626
Substrate
n/a
Meas. Tech.
ChEMBL_1284012 (CHEMBL3107076)
IC50
810±n/a nM
Citation
 Mittapalli, GK; Roberts, E Ligands of the neuropeptide Y Y2 receptor. Bioorg Med Chem Lett 24:430-41 (2014) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM50445626
Synonyms:
CHEMBL3104190
Type:
Small organic molecule
Emp. Form.:
C26H32FN5O
Mol. Mass.:
449.5636
SMILES:
CCN(CC)C(=O)C(N1CCN(CC1)c1ccc(cc1F)-c1cc(C)[nH]n1)c1ccccc1
Structure:
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