Reaction Details Report a problem with these data
Target
NADH-ubiquinone oxidoreductase chain 1
Ligand
BDBM50004702
Substrate
n/a
Meas. Tech.
ChEMBL_915023 (CHEMBL3059591)
IC50
2.0±n/a nM
Citation
  TBA Tetrahedron 60:10651-10657 (2004)    Article 
Target
Name:
NADH-ubiquinone oxidoreductase chain 1
Synonyms:
MT-ND1 | MTND1 | NADH Oxidase | NADH-ubiquinone oxidoreductase | NADH-ubiquinone oxidoreductase chain 1 | NADH1 | ND1 | NU1M_BOVIN
Type:
Protein
Mol. Mass.:
35672.63
Organism:
Bos taurus (Bovine)
Description:
P03887
Residue:
318
Sequence:
MFMINILMLIIPILLAVAFLTLVERKVLGYMQLRKGPNVVGPYGLLQPIADAIKLFIKEPLRPATSSASMFILAPIMALGLALTMWIPLPMPYPLINMNLGVLFMLAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSVLLMSGSFTLSTLITTQEQMWLILPAWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFMAEYANIIMMNIFTAILFLGTSHNPHMPELYTINFTIKSLLLTMSFLWIRASYPRFRYDQLMHLLWKNFLPLTLALCMWHVSLPILTSGIPPQT
  
Inhibitor
Name:
BDBM50004702
Synonyms:
(10S)-COROSSOLINE
Type:
Small organic molecule
Emp. Form.:
C35H64O6
Mol. Mass.:
580.8791
SMILES:
CCCCCCCCCCCC[C@@H](O)[C@H]1CC[C@@H](O1)[C@H](O)CCCC[C@@H](O)CCCCCCCC1=C[C@H](C)OC1=O |r,t:35|
Structure:
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