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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50016104
Substrate
n/a
Meas. Tech.
ChEMBL_1367301 (CHEMBL866116)
IC50
17440±n/a nM
Citation
 He, X; Chen, YY; Shi, JB; Tang, WJ; Pan, ZX; Dong, ZQ; Song, BA; Li, J; Liu, XH New coumarin derivatives: design, synthesis and use as inhibitors of hMAO. Bioorg Med Chem 22:3732-8 (2014) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50016104
Synonyms:
CHEMBL3261213
Type:
Small organic molecule
Emp. Form.:
C14H14N2O5
Mol. Mass.:
290.2714
SMILES:
CCC(C)NC(=O)c1cc2cc(ccc2oc1=O)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: