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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM23411
Substrate
n/a
Meas. Tech.
ChEMBL_1453700 (CHEMBL3364102)
EC50
16400±n/a nM
Citation
 Liu, Q; Yang, QM; Hu, HJ; Yang, L; Yang, YB; Chou, GX; Wang, ZT Bioactive diterpenoids and flavonoids from the aerial parts of Scoparia dulcis. J Nat Prod 77:1594-600 (2014) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
Nr1c3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG_MOUSE | Pparg
Type:
PROTEIN
Mol. Mass.:
57593.55
Organism:
Mus musculus
Description:
ChEMBL_1453700
Residue:
505
Sequence:
MGETLGDSPVDPEHGAFADALPMSTSQEITMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISAPHYEDIPFTRADPMVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNRPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKNIPGFINLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKNLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKVLQKMTDLRQIVTEHVQLLHVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM23411
Synonyms:
5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one | Scutel-larei | Scutellarein | Scutellarein (2) | Scutellarein (28) | US10252984, Table 2.2
Type:
flavone
Emp. Form.:
C15H10O6
Mol. Mass.:
286.2363
SMILES:
Oc1ccc(cc1)-c1cc(=O)c2c(O)c(O)c(O)cc2o1
Structure:
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