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Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50051068
Substrate
n/a
Meas. Tech.
ChEMBL_1446866 (CHEMBL3371937)
IC50
1400±n/a nM
Citation
 Romagnoli, R; Baraldi, PG; Salvador, MK; Prencipe, F; Bertolasi, V; Cancellieri, M; Brancale, A; Hamel, E; Castagliuolo, I; Consolaro, F; Porcù, E; Basso, G; Viola, G Synthesis, antimitotic and antivascular activity of 1-(3',4',5'-trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles. J Med Chem 57:6795-808 (2014) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50051068
Synonyms:
CHEMBL3318076
Type:
Small organic molecule
Emp. Form.:
C20H23N5O4
Mol. Mass.:
397.4277
SMILES:
CCc1ccc(Nc2nc(N)n(n2)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1
Structure:
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