Reaction Details Report a problem with these data
Target
Platelet-derived growth factor subunit B
Ligand
BDBM50059654
Substrate
n/a
Meas. Tech.
ChEMBL_1460665 (CHEMBL3395906)
Kd
<1000±n/a nM
Citation
 Koch, P; Gehringer, M; Laufer, SA Inhibitors of c-Jun N-terminal kinases: an update. J Med Chem 58:72-95 (2015) [PubMed]  Article 
Target
Name:
Platelet-derived growth factor subunit B
Synonyms:
PDGF | PDGF2 | PDGFB | PDGFB_HUMAN | Platelet-derived growth factor subunit B | Platelet-derived growth factor subunit B (PDGFB) | SIS
Type:
Enzyme
Mol. Mass.:
27298.80
Organism:
Homo sapiens (Human)
Description:
P01127
Residue:
241
Sequence:
MNRCWALFLSLCCYLRLVSAEGDPIPEELYEMLSDHSIRSFDDLQRLLHGDPGEEDGAELDLNMTRSHSGGELESLARGRRSLGSLTIAEPAMIAECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRKIEIVRKKPIFKKATVTLEDHLACKCETVAAARPVTRSPGGSQEQRAKTPQTRVTIRTVRVRRPPKGKHRKFKHTHDKTALKETLGA
  
Inhibitor
Name:
BDBM50059654
Synonyms:
CHEMBL2144409
Type:
Small organic molecule
Emp. Form.:
C28H26N8O
Mol. Mass.:
490.559
SMILES:
Cc1ccc(cn1)-c1ncn(n1)-c1ccc(Nc2nccc(n2)-c2cccc(c2)N2CCOCC2)cc1
Structure:
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