Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, heart
Ligand
BDBM50063854
Substrate
n/a
Meas. Tech.
ChEMBL_1463784 (CHEMBL3404794)
IC50
5160±n/a nM
Citation
 Cai, H; Liu, Q; Gao, D; Wang, T; Chen, T; Yan, G; Chen, K; Xu, Y; Wang, H; Li, Y; Zhu, W Novel fatty acid binding protein 4 (FABP4) inhibitors: virtual screening, synthesis and crystal structure determination. Eur J Med Chem 90:241-50 (2015) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, heart
Synonyms:
FABP11 | FABP3 | FABPH_HUMAN | Fatty acid binding protein muscle | MDGI
Type:
PROTEIN
Mol. Mass.:
14858.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1463784
Residue:
133
Sequence:
MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA
  
Inhibitor
Name:
BDBM50063854
Synonyms:
CHEMBL3400157
Type:
Small organic molecule
Emp. Form.:
C15H24O3S
Mol. Mass.:
284.414
SMILES:
CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(O)(=O)=O
Structure:
Search PDB for entries with ligand similarity: