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Target
Formyl peptide receptor-related sequence 1
Ligand
BDBM50071956
Substrate
n/a
Meas. Tech.
ChEMBL_1467726 (CHEMBL3411163)
EC50
9000±n/a nM
Citation
 Lacombe, C; Piesse, C; Sagan, S; Combadière, C; Rosenstein, Y; Auvynet, C Pachymodulin, a new functional formyl peptide receptor 2 peptidic ligand isolated from frog skin has Janus-like immunomodulatory capacities. J Med Chem 58:1089-99 (2015) [PubMed]  Article 
Target
Name:
Formyl peptide receptor-related sequence 1
Synonyms:
FMLP-R-I | FMLP-related receptor I | FPRS1_MOUSE | Formyl peptide receptor related sequence 1 | Formyl peptide receptor-like 1 | Fpr-s1 | Fpr2 | Fpr3 | Fprl1 | LXA4 receptor | Lipoxin A4 receptor | Lxa4r | N-formyl peptide receptor 2 | N-formyl peptide receptor 3
Type:
PROTEIN
Mol. Mass.:
39532.25
Organism:
Mus musculus
Description:
ChEMBL_109574
Residue:
351
Sequence:
METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI
  
Inhibitor
Name:
BDBM50071956
Synonyms:
CHEMBL3407845
Type:
Small organic molecule
Emp. Form.:
C27H51N7O10
Mol. Mass.:
633.7347
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)C(O)=O |r|
Structure:
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