Reaction Details Report a problem with these data
Target
Similar to alpha-tubulin isoform 1
Ligand
BDBM50086283
Substrate
n/a
Meas. Tech.
ChEMBL_1475978 (CHEMBL3428203)
IC50
>40000±n/a nM
Citation
 Qin, YJ; Li, YJ; Jiang, AQ; Yang, MR; Zhu, QZ; Dong, H; Zhu, HL Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors. Eur J Med Chem 94:447-57 (2015) [PubMed]  Article 
Target
Name:
Similar to alpha-tubulin isoform 1
Synonyms:
Similar to alpha-tubulin isoform 1
Type:
PROTEIN
Mol. Mass.:
10383.05
Organism:
Bos taurus
Description:
ChEMBL_104716
Residue:
99
Sequence:
CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
  
Inhibitor
Name:
BDBM50086283
Synonyms:
CHEMBL3426010
Type:
Small organic molecule
Emp. Form.:
C24H19BrN2O4
Mol. Mass.:
479.323
SMILES:
COc1cccc(c1)C1=NN(C(C1)c1ccc2OCOc2c1)C(=O)c1ccc(Br)cc1 |t:9|
Structure:
Search PDB for entries with ligand similarity: