Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM50088345
Substrate
n/a
Meas. Tech.
ChEMBL_1476957 (CHEMBL3430212)
Kd
3000±n/a nM
Citation
 Magee, TV Progress in discovery of small-molecule modulators of protein-protein interactions via fragment screening. Bioorg Med Chem Lett 25:2461-8 (2015) [PubMed]  Article 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM50088345
Synonyms:
CHEMBL3427780
Type:
Small organic molecule
Emp. Form.:
C26H24N2O3
Mol. Mass.:
412.4804
SMILES:
O=C(OCCc1ccccc1)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: