Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50097908
Substrate
n/a
Meas. Tech.
ChEMBL_1502292 (CHEMBL3591526)
Ki
2.1±n/a nM
Citation
 Keck, TM; John, WS; Czoty, PW; Nader, MA; Newman, AH Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis. J Med Chem 58:5361-80 (2015) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50097908
Synonyms:
CHEMBL3590086
Type:
Small organic molecule
Emp. Form.:
C23H27ClN4O3
Mol. Mass.:
442.938
SMILES:
Cc1ccc(Cl)c(c1)N1CCN(CCCCNC(=O)c2ccc3oc(=O)[nH]c3c2)CC1
Structure:
Search PDB for entries with ligand similarity: