Reaction Details Report a problem with these data
Target
P2Y purinoceptor 14
Ligand
BDBM50097952
Substrate
n/a
Meas. Tech.
ChEMBL_1502487 (CHEMBL3592309)
EC50
5160000±n/a nM
Citation
 Trujillo, K; Paoletta, S; Kiselev, E; Jacobson, KA Molecular modeling of the human P2Y14 receptor: A template for structure-based design of selective agonist ligands. Bioorg Med Chem 23:4056-64 (2015) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 14
Synonyms:
GPR105 | Insulin Receptor-Related Protein (INSRR) | KIAA0001 | P2RY14 | P2Y14_HUMAN | Purinergic receptor P2Y14
Type:
PROTEIN
Mol. Mass.:
38991.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1502487
Residue:
338
Sequence:
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
  
Inhibitor
Name:
BDBM50097952
Synonyms:
CHEMBL1199733
Type:
Small organic molecule
Emp. Form.:
C15H24N2O12P2
Mol. Mass.:
486.3048
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OC2CCCCC2)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure:
Search PDB for entries with ligand similarity: