Reaction Details Report a problem with these data
Target
Calmodulin
Ligand
BDBM50165124
Substrate
n/a
Meas. Tech.
ChEMBL_1576537 (CHEMBL3803977)
Kd
850±n/a nM
Citation
 Bruno, C; Cavalluzzi, MM; Rusciano, MR; Lovece, A; Carrieri, A; Pracella, R; Giannuzzi, G; Polimeno, L; Viale, M; Illario, M; Franchini, C; Lentini, G The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II. Eur J Med Chem 116:36-45 (2016) [PubMed]  Article 
Target
Name:
Calmodulin
Synonyms:
CALM | CALM_BOVIN | CAM
Type:
PROTEIN
Mol. Mass.:
16813.73
Organism:
Bos taurus
Description:
ChEMBL_1458985
Residue:
149
Sequence:
MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
  
Inhibitor
Name:
BDBM50165124
Synonyms:
CHEMBL3798296
Type:
Small organic molecule
Emp. Form.:
C28H37N3O
Mol. Mass.:
431.6129
SMILES:
COc1cccc(CN(CCN(CCN(C)C)Cc2ccccc2)Cc2ccccc2)c1
Structure:
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