Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50165202
Substrate
n/a
Meas. Tech.
ChEMBL_1572971 (CHEMBL3801685)
Ki
4000±n/a nM
Citation
 Lütnant, I; Schepmann, D; Wünsch, B Benzimidazolone bioisosteres of potent GluN2B selective NMDA receptor antagonists. Eur J Med Chem 116:136-146 (2016) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50165202
Synonyms:
CHEMBL3797704
Type:
Small organic molecule
Emp. Form.:
C23H29N3O
Mol. Mass.:
363.4959
SMILES:
Cn1c2cc3CCCC(Cc3cc2n(C)c1=O)NCCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: