Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50171870
Substrate
n/a
Meas. Tech.
ChEMBL_1577058 (CHEMBL3807104)
EC50
1280±n/a nM
Citation
 Krasavin, M; Lukin, A; Zhurilo, N; Kovalenko, A; Zahanich, I; Zozulya, S; Moore, D; Tikhonova, IG Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold. Bioorg Med Chem 24:2954-2963 (2016) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50171870
Synonyms:
CHEMBL3805879
Type:
Small organic molecule
Emp. Form.:
C18H14FN3O3S
Mol. Mass.:
371.385
SMILES:
OC(=O)CCc1nnc(s1)C(=O)Nc1cccc(c1)-c1ccc(F)cc1
Structure:
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