Reaction Details Report a problem with these data
Target
Inosine-uridine preferring nucleoside hydrolase
Ligand
BDBM50187703
Substrate
n/a
Meas. Tech.
ChEMBL_1589257 (CHEMBL3830285)
Ki
5400±n/a nM
Citation
 Wróblewski, AE; Glowacka, IE; Piotrowska, DG 1'-Homonucleosides and their structural analogues: A review. Eur J Med Chem 118:121-42 (2016) [PubMed]  Article 
Target
Name:
Inosine-uridine preferring nucleoside hydrolase
Synonyms:
IU-NH | IU-nucleoside hydrolase | IUNH | IUNH_CRIFA | Inosine-uridine preferring nucleoside hydrolase | Non-specific nucleoside hydrolase | Purine nucleosidase
Type:
PROTEIN
Mol. Mass.:
34318.86
Organism:
Crithidia fasciculata
Description:
ChEMBL_116821
Residue:
315
Sequence:
MPKKIILDCDPGLDDAVAILLAHGNPEIELLAITTVVGNQTLAKVTRNAQLVADIAGITGVPIAAGCDKPLVRKIMTAGHIHGESGMGTVAYPAEFKNKVDERHAVNLIIDLVMSHEPKTITLVPTGGLTNIAMAARLEPRIVDRVKEVVLMGGGYHEGNATSVAEFNIIIDPEAAHIVFNESWQVTMVGLDLTHQALATPPILQRVKEVDTNPARFMLEIMDYYTKIYQSNRYMAAAAVHDPCAVAYVIDPSVMTTERVPVDIELTGKLTLGMTVADFRNPRPEHCHTQVAVKLDFEKFWGLVLDALERIGDPQ
  
Inhibitor
Name:
BDBM50187703
Synonyms:
CHEMBL3827853
Type:
Small organic molecule
Emp. Form.:
C11H15N5O4
Mol. Mass.:
281.2679
SMILES:
OC[C@H]1N[C@@H](Cn2cnc3c(O)ncnc23)[C@H](O)[C@@H]1O |r|
Structure:
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