Reaction Details Report a problem with these data
Target
Iron-starvation protein PigA
Ligand
BDBM50191302
Substrate
n/a
Meas. Tech.
ChEMBL_1612785 (CHEMBL3854585)
Kd
7000±n/a nM
Citation
 Heinzl, GA; Huang, W; Yu, W; Giardina, BJ; Zhou, Y; MacKerell, AD; Wilks, A; Xue, F Iminoguanidines as Allosteric Inhibitors of the Iron-Regulated Heme Oxygenase (HemO) of Pseudomonas aeruginosa. J Med Chem 59:6929-42 (2016) [PubMed]  Article 
Target
Name:
Iron-starvation protein PigA
Synonyms:
Heme oxygenase | Iron-starvation protein PigA
Type:
PROTEIN
Mol. Mass.:
21946.19
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_444781
Residue:
198
Sequence:
MDTLAPESTRQNLRSQRLNLLTNEPHQRLESLVKSKEPFASRDNFARFVAAQYLFQHDLEPLYRNEALARLFPGLASRARDDAARADLADLGHPVPEGDQSVREADLSLAEALGWLFVSEGSKLGAAFLFKKAAALELDENFGARHLAEPEGGRAQGWKSFVAILDGIELNEEEERLAAKGASDAFNRFGDLLERTFA
  
Inhibitor
Name:
BDBM50191302
Synonyms:
4-Chlorobenzaldehyde [Amino(Lambda~5~-Azanylidene)Methyl]Hydrazone Chloride Salt | Amino(2-(4-Chlorobenzylidene)Hydrazinyl)Methaniminium Chloride | CHEMBL54151
Type:
Small organic molecule
Emp. Form.:
C8H10Cl2N4
Mol. Mass.:
233.098
SMILES:
Cl.NC(=N)N\N=C\c1ccc(Cl)cc1
Structure:
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