Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM50212635
Substrate
n/a
Meas. Tech.
ChEMBL_40896 (CHEMBL653649)
IC50
7.61±n/a nM
Citation
  TBA Bioorg Med Chem Lett 3:2247-2252 (1993)   
Target
Name:
Beta-lactamase
Synonyms:
BLAC_PROMI | Beta-lactamase | Carbenicillinase | blaP
Type:
PROTEIN
Mol. Mass.:
32766.94
Organism:
Proteus mirabilis
Description:
ChEMBL_101534
Residue:
298
Sequence:
MNVRQHKASFFSVVITFLCLTLSLNANATDSVLEAVTNAETELGARIGLAAHDLETGKRWEHKSNERFPLSSTFKTLACANVLQRVDLGKERIDRVVRFSESNLVTYSPVTEKHVGKKGMSLAELCQATLSTSDNSAANFILQAIGGPKALTKFLRSIGDDTTRLDRWEPELNEAVPGDKRDTTTPIAMVTTLEKLLIDETLSIKSRQQLESWLKGNEVGDALFRKGVPSDWIVADRTGAGGYGSRAITAVMWPPNRKPIVAALYITETDASFEERNAVIAKIGEQIAKTVLMENSRN
  
Inhibitor
Name:
BDBM50212635
Synonyms:
CHEMBL415266
Type:
Small organic molecule
Emp. Form.:
C10H12BrN5O3S2
Mol. Mass.:
394.268
SMILES:
[H][C@]12S[C@@](C)(CSc3nnnn3C)[C@@H](N1C(=O)[C@H]2Br)C(O)=O
Structure:
Search PDB for entries with ligand similarity: