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Target
Protein kinase C zeta type
Ligand
BDBM50217034
Substrate
n/a
Meas. Tech.
ChEMBL_162387 (CHEMBL767475)
IC50
>1000000±n/a nM
Citation
 Xu, WC; Zhou, Q; Ashendel, CL; Chang, CT; Chang, CJ Novel protein kinase C inhibitors: synthesis and PKC inhibition of beta-substituted polythiophene derivatives. Bioorg Med Chem Lett 9:2279-82 (1999) [PubMed]  Article 
Target
Name:
Protein kinase C zeta type
Synonyms:
KPCZ_RAT | Pkcz | Prkcz | Protein kinase C (PKC) | Protein kinase C zeta type | nPKC-zeta
Type:
PROTEIN
Mol. Mass.:
67722.31
Organism:
Rattus norvegicus
Description:
ChEMBL_104731
Residue:
592
Sequence:
MPSRTDPKMDRSGGRVRLKAHYGGDILITSVDPTTTFQDLCEEVRDMCGLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLACQGRDEVLIIHVFPSIPEQPGMPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHVLVPLTCRRHMDSVMPSQEPPVDDKNDGVDLPSEETDGIAYISSSRKHDNIKDDSEDLKPVIDGVDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQTLPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDEDVIKRIDQSEFEGFEYINPLLLSAEESV
  
Inhibitor
Name:
BDBM50217034
Synonyms:
CHEMBL310913
Type:
Small organic molecule
Emp. Form.:
C9H8OS2
Mol. Mass.:
196.289
SMILES:
OCc1csc(c1)-c1cccs1
Structure:
Search PDB for entries with ligand similarity: