Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50232515
Substrate
n/a
Meas. Tech.
ChEBML_1647919
EC50
50±n/a nM
Citation
 Sparks, SM; Aquino, C; Banker, P; Collins, JL; Cowan, D; Diaz, C; Dock, ST; Hertzog, DL; Liang, X; Swiger, ED; Yuen, J; Chen, G; Jayawickreme, C; Moncol, D; Nystrom, C; Rash, V; Rimele, T; Roller, S; Ross, S Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist. Bioorg Med Chem Lett 27:1278-1283 (2017) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50232515
Synonyms:
CHEMBL4084333
Type:
Small organic molecule
Emp. Form.:
C18H19BrO3
Mol. Mass.:
363.246
SMILES:
Cc1ccc(Br)c(COc2ccc(CCC(O)=O)cc2C)c1
Structure:
Search PDB for entries with ligand similarity: