Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM50232532
Substrate
n/a
Meas. Tech.
ChEMBL_1647919 (CHEMBL3996975)
EC50
40±n/a nM
Citation
 Sparks, SM; Aquino, C; Banker, P; Collins, JL; Cowan, D; Diaz, C; Dock, ST; Hertzog, DL; Liang, X; Swiger, ED; Yuen, J; Chen, G; Jayawickreme, C; Moncol, D; Nystrom, C; Rash, V; Rimele, T; Roller, S; Ross, S Exploration of phenylpropanoic acids as agonists of the free fatty acid receptor 4 (FFA4): Identification of an orally efficacious FFA4 agonist. Bioorg Med Chem Lett 27:1278-1283 (2017) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM50232532
Synonyms:
CHEMBL4103243
Type:
Small organic molecule
Emp. Form.:
C24H24O4
Mol. Mass.:
376.445
SMILES:
Cc1cc(COc2ccc(CCC(O)=O)cc2C)cc(Oc2ccccc2)c1
Structure:
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