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Target
D(2) dopamine receptor
Ligand
BDBM84637
Substrate
n/a
Meas. Tech.
ChEMBL_1660565 (CHEMBL4010177)
EC50
295±n/a nM
Citation
 Möller, D; Banerjee, A; Uzuneser, TC; Skultety, M; Huth, T; Plouffe, B; Hübner, H; Alzheimer, C; Friedland, K; Müller, CP; Bouvier, M; Gmeiner, P Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. J Med Chem 60:2908-2929 (2017) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM84637
Synonyms:
CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPIROLE | Quinpirole,(-) | US9359372, Quinpirole
Type:
Small organic molecule
Emp. Form.:
C13H21N3
Mol. Mass.:
219.3259
SMILES:
CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r|
Structure:
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