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Target
Tyrosinase
Ligand
BDBM50237229
Substrate
n/a
Meas. Tech.
ChEMBL_1660839 (CHEMBL4010451)
IC50
5000±n/a nM
Citation
 Santi, MD; Peralta, MA; Mendoza, CS; Cabrera, JL; Ortega, MG Chemical and bioactivity of flavanones obtained from roots of Dalea pazensis Rusby. Bioorg Med Chem Lett 27:1789-1794 (2017) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
TYRO_MOUSE | Tyr
Type:
Protein
Mol. Mass.:
60600.74
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
533
Sequence:
MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
  
Inhibitor
Name:
BDBM50237229
Synonyms:
CHEMBL4083227
Type:
Small organic molecule
Emp. Form.:
C26H30O6
Mol. Mass.:
438.5128
SMILES:
[#6]-[#8]-c1cc(-[#8])c(cc1-[#6]-1-[#6]-[#6](=O)-c2c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])cc2-[#8]-1)C([#6])([#6])[#6]=[#6]
Structure:
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