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Target
Glutamate receptor
Ligand
BDBM50289504
Substrate
n/a
Ki
2150±n/a nM
Comments
PDSP_554
Citation
 Toms, NJ; Reid, ME; Phillips, W; Kemp, MC; Roberts, PJ A novel kainate receptor ligand [3H]-(2S,4R)-4-methylglutamate: pharmacological characterization in rabbit brain membranes. Neuropharmacology 36:1483-8 (1997) [PubMed]  Article 
Target
Name:
Glutamate receptor
Synonyms:
Glutamate kainate | Glutamate-Kainate
Type:
Enzyme Catalytic Domain
Mol. Mass.:
96238.98
Organism:
RABBIT
Description:
Glutamate-Kainate Glutamate kainate RABBIT::G1SXH9
Residue:
849
Sequence:
MPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEAQWDGLTGRITFNKTDGLRKNFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTEGNKDRSNNITDSLANRTLIVTTILEEPYVMYKKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHKADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDVEQCLSFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA
  
Inhibitor
Name:
BDBM50289504
Synonyms:
7-Cyano-3-hydroxy-6-nitro-quinoxalin-2-ol anion | CNQX
Type:
Small organic molecule
Emp. Form.:
C9H3N4O4
Mol. Mass.:
231.1451
SMILES:
[O-][N+](=O)c1cc2[n-]c(=[OH+])c(=O)[n-]c2cc1C#N
Structure:
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