Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50005247
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_1170
Citation
 Toll, L; Berzetei-Gurske, IP; Polgar, WE; Brandt, SR; Adapa, ID; Rodriguez, L; Schwartz, RW; Haggart, D; O'Brien, A; White, A; Kennedy, JM; Craymer, K; Farrington, L; Auh, JS Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr 178:440-66 (1998) [PubMed] 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50005247
Synonyms:
(+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | (-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | (R)-(-)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | (S)-(+)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | 2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine | 2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine((R)-(-)-MDA) | 3,4-methylenedioxyamphetamine | CHEMBL6731 | MDA | MDA, (R,S) | MDA,R(-) | Tenamfetamine | methylenedioxyamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H13NO2
Mol. Mass.:
179.2157
SMILES:
CC(N)Cc1ccc2OCOc2c1
Structure:
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