Reaction Details Report a problem with these data
Target
Galanin receptor type 1
Ligand
BDBM50307254
Substrate
n/a
Ki
2.40±n/a nM
Comments
PDSP_1162
Citation
 Borowsky, B; Walker, MW; Huang, LY; Jones, KA; Smith, KE; Bard, J; Branchek, TA; Gerald, C Cloning and characterization of the human galanin GALR2 receptor. Peptides 19:1771-81 (1998) [PubMed]  Article 
Target
Name:
Galanin receptor type 1
Synonyms:
GAL1-R | GALNR | GALNR1 | GALR1 | GALR1_HUMAN | Galanin R1 | Galanin receptor 1 | Galanin receptor type 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38976.60
Organism:
Homo sapiens (Human)
Description:
Galanin R1 GALR1 HUMAN::P47211
Residue:
349
Sequence:
MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
  
Inhibitor
Name:
BDBM50307254
Synonyms:
CHEMBL604990 | GWTLNSAGYLLGPPPALALA-CONH2 | M40
Type:
Small organic molecule
Emp. Form.:
C94H145N23O24
Mol. Mass.:
1981.2968
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)CN)[C@@H](C)O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O |r|
Structure:
Search PDB for entries with ligand similarity: