Reaction Details Report a problem with these data
Target
Neuromedin-B receptor
Ligand
BDBM85483
Substrate
n/a
Ki
47±n/a nM
Comments
PDSP_1487
Citation
 Katsuno, T; Pradhan, TK; Ryan, RR; Mantey, SA; Hou, W; Donohue, PJ; Akeson, MA; Spindel, ER; Battey, JF; Coy, DH; Jensen, RT Pharmacology and cell biology of the bombesin receptor subtype 4 (BB4-R). Biochemistry 38:7307-20 (1999) [PubMed]  Article 
Target
Name:
Neuromedin-B receptor
Synonyms:
NMB | NMBR_RAT | Neuromedin B receptor | Neuromedin-B receptor | Nmbr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43540.92
Organism:
RAT
Description:
NMB 0 RAT::P24053
Residue:
390
Sequence:
MPPRSLPNLSLPTEASESELEPEVWENDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVVLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSSDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIRSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHILYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCGQKSYPERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNGHSTKQEIAL
  
Inhibitor
Name:
BDBM85483
Synonyms:
CAS_5748287 | NSC_5748287 | Phyllolitorin
Type:
Small organic molecule
Emp. Form.:
C49H69N11O11S
Mol. Mass.:
1020.204
SMILES:
CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(NC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)C1CCC(=O)N1)C(C)C)C(N)=O
Structure:
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