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Target
Alpha-2A adrenergic receptor
Ligand
BDBM81979
Substrate
n/a
Ki
57.54±n/a nM
Comments
PDSP_914
Citation
 Brink, CB; Wade, SM; Neubig, RR Agonist-directed trafficking of porcine alpha(2A)-adrenergic receptor signaling in Chinese hamster ovary cells: l-isoproterenol selectively activates G(s). J Pharmacol Exp Ther 294:539-47 (2000) [PubMed] 
Target
Name:
Alpha-2A adrenergic receptor
Synonyms:
Alpha-2A adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48998.96
Organism:
PIG
Description:
adrenergic Alpha2 0 PIG::P18871
Residue:
450
Sequence:
MGSLQPEAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKAGGGGQQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAAAALPGGAERRPNGLGPERGVGRVGAEAEPLPVQLNGAPGEPAPAGPRDADGLDLEESSSSEHAERPPGPRRSERGPRAKSKARASQVKPGDSLPRRGPGAPGPGAPATGAGEERGGVAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
  
Inhibitor
Name:
BDBM81979
Synonyms:
CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanabenz | NSC_3517 | NSC_65636
Type:
Small organic molecule
Emp. Form.:
C8H8Cl2N4
Mol. Mass.:
231.082
SMILES:
[#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl |w:5.5|
Structure:
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