Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM50334460
Substrate
n/a
Ki
19.5±n/a nM
Comments
PDSP_1635
Citation
 Rothman, RB; Baumann, MH; Dersch, CM; Romero, DV; Rice, KC; Carroll, FI; Partilla, JS Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin. Synapse 39:32-41 (2001) [PubMed]  Article 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM50334460
Synonyms:
((1R,2S,3S,5S)-3-(4-iodophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl)(pyrrolidin-1-yl)methanone | CHEMBL1643896 | RTI-229
Type:
Small organic molecule
Emp. Form.:
C19H25IN2O
Mol. Mass.:
424.3191
SMILES:
CN1[C@H]2CC[C@@H]1[C@H]([C@H](C2)c1ccc(I)cc1)C(=O)N1CCCC1 |r,TLB:0:1:7.8.6:3.4|
Structure:
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