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Target
Melanocortin receptor 4
Ligand
BDBM71009
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64634±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM71009
Synonyms:
2-chloranyl-1-(1-cyclohexylcarbonyl-2,3-dihydroindol-5-yl)ethanone | 2-chloro-1-[1-(cyclohexanecarbonyl)-2,3-dihydroindol-5-yl]ethanone | 2-chloro-1-[1-(cyclohexanecarbonyl)indolin-5-yl]ethanone | 2-chloro-1-[1-[cyclohexyl(oxo)methyl]-2,3-dihydroindol-5-yl]ethanone | MLS000706374 | SMR000288426 | cid_1447917
Type:
Small organic molecule
Emp. Form.:
C17H20ClNO2
Mol. Mass.:
305.799
SMILES:
ClCC(=O)c1ccc2N(CCc2c1)C(=O)C1CCCCC1
Structure:
Search PDB for entries with ligand similarity: