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Target
Dual specificity protein phosphatase 3
Ligand
BDBM82711
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
3900±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82711
Synonyms:
MLS000581278 | N-(4-{[2-(3-phenylpropanoyl)hydrazino]carbonyl}phenyl)benzamide | N-[4-[(3-phenylpropanoylamino)carbamoyl]phenyl]benzamide | N-[4-[(hydrocinnamoylamino)carbamoyl]phenyl]benzamide | N-[4-[oxo-[(1-oxo-3-phenylpropyl)hydrazo]methyl]phenyl]benzamide | SMR000199892 | cid_2207747
Type:
Small organic molecule
Emp. Form.:
C23H21N3O3
Mol. Mass.:
387.4311
SMILES:
O=C(CCc1ccccc1)NNC(=O)c1ccc(NC(=O)c2ccccc2)cc1
Structure:
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