Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89047
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
20510±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89047
Synonyms:
MLS-0454717.0001 | [(Z)-[(4-bromophenyl)-morpholin-4-yl-methylidene]amino] benzoate | [(Z)-[(4-bromophenyl)-morpholin-4-ylmethylidene]amino] benzoate | benzoic acid [(Z)-[(4-bromophenyl)-(4-morpholinyl)methylidene]amino] ester | benzoic acid [(Z)-[(4-bromophenyl)-morpholino-methylene]amino] ester | cid_5337954
Type:
Small organic molecule
Emp. Form.:
C18H17BrN2O3
Mol. Mass.:
389.243
SMILES:
Brc1ccc(cc1)C(=N\OC(=O)c1ccccc1)\N1CCOCC1
Structure:
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