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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM64734
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
5320±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM64734
Synonyms:
4-Bromo-N-[N'-(4-nitro-benzoyl)-hydrazinocarbothioyl]-benzamide | 4-bromanyl-N-[[(4-nitrophenyl)carbonylamino]carbamothioyl]benzamide | 4-bromo-N-[[(4-nitrobenzoyl)amino]carbamothioyl]benzamide | 4-bromo-N-[[(4-nitrobenzoyl)amino]thiocarbamoyl]benzamide | 4-bromo-N-[[[(4-nitrophenyl)-oxomethyl]hydrazo]-sulfanylidenemethyl]benzamide | MLS001205111 | SMR000516966 | cid_3132901
Type:
Small organic molecule
Emp. Form.:
C15H11BrN4O4S
Mol. Mass.:
423.241
SMILES:
[O-][N+](=O)c1ccc(cc1)C(=O)NNC(=S)NC(=O)c1ccc(Br)cc1
Structure:
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